Directions(1-10): In the following passage there are blanks, each of which has been numbered. These numbers are printed below the passage and against each, five words are suggested, one of which fits the blank appropriately. Find out the appropriate word in each case.
In a major breakthrough, a team of researchers, _(1)_ one of Indian origin, has identified two chemicals that can help _(2)_ heart cells that can beat harder, faster and stronger, bringing technology one step closer to regenerating damaged hearts. Scientists from Gladstone Institute of Cardiovascular Disease, in San Francisco, US, tested 5,500 chemicals, and identified two that can potentially transform a scar tissue into healthy beating heart muscle -- a discovery that can help find new and _(3)_ treatments for heart failure. The two chemicals _(4)_eightfold the number of heart cells created, as well as sped up the process of cell conversion, achieving in one week what used to take six to eight weeks, the study said.
"The study discovered that _(5)_ inhibiting two biological pathways active in embryonic formation _(6)_ the speed, quantity, and quality of the heart cells produced from our original process," said senior author, Director of the Gladstone Institute of Cardiovascular Disease. After suffering a heart attack, the connective _(7)_ develop scar tissue, which then contribute to heart failure. When the heart muscle gets _(8)_, the body is unable to repair the dead or injured cells. According to researchers, the first chemical inhibits a growth factor that helps cells grow and divide and is important for repairing tissue after injury. The second chemical inhibits an important pathway that regulates heart development.
By combining the two chemicals with the current method -- of reprogramming connective tissue cells into heart muscle cells using certain proteins -- the researchers _(9)_ regenerated heart muscle and greatly improved heart function in mice that had suffered a heart attack. In addition, the chemicals were also used to improve direct cardiac reprogramming of human cells, which is a more complicated _(10)_ that requires additional factors, the researchers noted in the paper published in the journal Circulation.
Q.1- (1) containing (2) in addition to (3) among (4) including (5) rejecting
Q.2- (1) decline (2) growing (3) flourishing (4) stunt (5) develop
Q.3- (1) productivity (2) impotent (3) effective (4) agile (5) ambidextrous
Q.4- (1) increased (2) additional (3) augment (4) raise (5) elevating
Q.5- (1) hilarious (2) chemically (3) chaotically (4) illustrations (5) supremely
Q.6- (1) improves (2) meliorate (3) develop (4) reduces (5) upgraded
Q.7- (1) grain (2) weave (3) twill (4) edging (5) tissues
Q.8- (1) rogue (2) damaged (3) ironical (4) impair (5) mended
Q.9- (1) successfully (2) favourable (3) opportunely (4) profitably (5) auspicious
Q.10- (1) boisterous (2) motive (3) sloth (4) process (5) foment
ANSWER
1- ANSWER – (4)
For Other Option – rejecting- say no to
2- ANSWER – (5)
For Other Options – flourishing- prospering, stunt- trick
3- ANSWER – (3)
For Other Options – agile- deft, ambidextrous- insincere, impotent- disabled
4- ANSWER – (1)
For Other Options – augment- improve, elevating- lift up
5- ANSWER – (2)
For Other Options – hilarious- very funny, chaotically- inarticulately
6- ANSWER – (1)
For Other Option – meliorate- get or make better
7- ANSWER – (5)
For Other Options – twill- fabric, edging- border
8- ANSWER – (2)
For Other Options – rogue- person who deceives, ironical- cynical
9- ANSWER – (1)
For Other Options – auspicious- favourable, opportunely- relevantly
10- ANSWER – (4)
For Other Options – boisterous- noisy and mischievous, sloth- laziness, foment- instigate
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MAHENDRA GURU